PEMF Scientific Extracts

Below are selected some selected scientific abstracts addressing pulsating electromagnetic field therapy, electromagnetism, magneticresonance stimulation, electrosmog and dirty electricity are posted throughout the NTA site. As a member of the Nutritional Therapeutics Association you will have access to a wider amount of practical information. 

Overall Scientific papers on the viability of PEMF therapies.

Peer Reviewed MRS(PEMF) Studies

Therapeutic Uses of ElectroMagnetic Fields

Review of Therapeutic Uses of PEMF

 The effect of pulsed electromagnetic fields in the treatment of cervical osteoarthritis: a randomized, double-blind, sham-controlled trial:

Sutbeyaz, Sezer and Koseoglu. The effect of pulsed electromagnetic fileds in the treatment of cervical osteoarthritis: a randomized, double-blind, sham-controlled trial. Rheumatology International 2006; 26:320-324. Copy Available to NTA Members

Pulsed electromagnetic field therapy in the management of knee OA:

Pfeiffer K. Pulsed electromagnetic field therapy in the management of knee osteoarthritis. Annals of Rheumatological Disorders 2001; 60:717. Copy Available to NTA Members

Biochemical and morphological study of human articular chondrocytes cultivated in the presence of pulsed signal therapy:

Fioravanti A, Nerucci F, Collodel G, et al. Biochemical and morphological study of human articular chondrocytes cultivated in the present of pulsed signal therapy. Annals of Rheumatological Disorders 2006; 61:1032-33. Copy Available to NTA Members

The effectiveness of pulsed electrical stimulation (E-PES) in the management of osteoarthritis of the knee: a protocol for a randomised controlled trial:

Fary RE, Carroll GJ, Briff TG, et al. The effectiveness of pulsed electrical stimulation (E-PES) in the management of osteoarthritis of the knee: a protocol for a randomized controlled trial. BioMed Central Musculoskeletal Disorders 2008; 9:18. Copy Available to NTA Members

Nanosecond pulsed electric fields cause melanomas to selfdestruct:

Nuccitelli R, Pliquett U, Chen X, et al. Nanosecond pulsed electric fields cause melanomas to self-destruct. Biochem Biophys Res Commun 2006 (May 5); 343 (2): 351-360. Copy Available to NTA Members

free abstracts:

Electromagnetic interventions in musculoskeletal disorders

Bachl, N., G. Ruoff, et al. (2008). “Electromagnetic interventions in musculoskeletal disorders.” Clin Sports Med 27(1): 87-105, viii.

Electromagnetic interventions in general and those considering the musculoskeletal system in particular hold many obscurities. Several studies revealing positive effects of electromagnetic fields oppose those showing no beneficial effects. After a historical review and a discussion of basic details on electromagnetic signals, this article provides information on the effects of electromagnetic fields on a cellular level and gives an account of preclinical and clinical studies focused on electromagnetic interventions by means of weak pulsed electromagnetic fields on musculoskeletal disorders.

Pulsed magnetic field therapy for osteoarthritis of the knee

Nicolakis P, Kollmitzer J, Crevenna R, Bittner C, Erdogmus CB, Nicolakis J. Pulsed magnetic field therapy for osteoarthritis of the knee–a double-blind sham-controlled trial. Wien Klin Wochenschr. 2002 Aug 30;114(15-16):678-84.

BACKGROUND AND METHODS: Pulsed magnetic field therapy is frequently used to treat the symptoms of osteoarthritis, although its efficacy has not been proven. We conducted a randomized, double-blind comparison of pulsed magnetic field and sham therapy in patients with symptomatic osteoarthritis of the knee. Patients were assigned to receive 84 sessions, each with a duration of 30 minutes, of either pulsed magnetic field or sham treatment. Patients administered the treatment on their own at home, twice a day for six weeks. RESULTS: According to a sample size estimation, 36 consecutive patients were enrolled. 34 patients completed the study, two of whom had to be excluded from the statistical analysis, as they had not applied the PMF sufficiently. Thus, 15 verum and 17 sham-treated patients were enrolled in the statistical analysis. After six weeks of treatment the WOMAC Osteoarthritis Index was reduced in the pulsed magnetic field-group from 84.1 (+/- 45.1) to 49.7 (+/- 31.6), and from 73.7 (+/- 43.3) to 66.9 (+/- 52.9) in the sham-treated group (p = 0.03). The following secondary parameters improved in the pulsed magnetic field group more than they did in the sham group: gait speed at fast walking [+6.0 meters per minute (1.6 to 10.4) vs. -3.2 (-8.5 to 2.2)], stride length at fast walking [+6.9 cm (0.2 to 13.7) vs. -2.9 (-8.8 to 2.9)], and acceleration time in the isokinetic dynamometry strength tests [-7.0% (-15.2 to 1.3) vs. 10.1% (-0.3 to 20.6)]. CONCLUSION: In patients with symptomatic osteoarthritis of the knee, PMF treatment can reduce impairment in activities of daily life and improve knee function.

Objective: To assess the effectiveness of pulsed electromagnetic fileds compared with placebo in the management of osteoarthritis of the knee.
Data sources: A systematic review of PubMed, EMBASE, and the Cochrane Controlled Trials Reister.
Methods: Randomized, controlled trials reporting on the blinded comparison of pulsed electromagnetic fields with placebo were included. Validity was tested according to the Jada Scale. Studies were pooled using fixed-effects and random-effects models after exclusion of publication bias and assessment of heterogeneity. Sensitivity analyses and meta-regression were performed to test the stability of our findings.
Results: Nine studies, including 483 patients, were pooled. No significant difference could be shown for pain (weighted mean difference 0.2 patients; 95% confidence interval (CI): -0.4 to 0.8) or stiffness (weighted mean difference 0.3; 95% CI: -0.3 to 0.9). There was a significant effect on activities of daily living (weighted mean difference 0.8; 95% CI 0.2—1.4, p = 0.014) and socres (standardized mean difference 0.4; 95% CI: 0.05—0.8, p=0.029). We saw only statistically insignificant differences between studies with different treatment protocols.
Conclusion: Pulsed electromagnetic fields improve clinical scores and function in patients with osteoarthritis of the knee and should be considered as adjuvant therapies in their management. There is still equipoise of evidence for an effect on pain in the current literature.

Interference of Programmed Electromagnetic Stimulation

Marianne Gwechenberger, Friedrich Rauscha,1 Gunter Stix, Gernot Schmid and Jeanette Strametz-Juranek. Interference of Programmed Electromagnetic Stimulation with Pacemakers and Automatic Implantable Cardioverter Defibrillators. Bioelectromagnetics 2006; 27:365-377.

A commercially available magnetic therapy system, designed for clinical application as well as for private use without medical supervision, was examined with respect to its potential for causing electromagnetic interference with implantable pacemakers (PMs) and automatic implantable cardioverter defibrillators (AICDs). A sample of 15 PMs and 5 AICDs were experimentally investigated. Each of the implants was realistically positioned in a homogeneous, electrically passive torso phantom and exposed to the magnetic fields of the system’s applicators (whole body mat, cushion, and bar applicator). The detection thresholds of the implants were programmed to maximum sensitivity and both unipolar as well as bipolar electrode configurations were considered. The evaluation of possible interferences was derived from the internal event storages and pacing statistics recorded by the implants during exposure. Any ‘‘heart activity’’ recorded by the implants during exposure was interpreted as a potential interference, because the implant obviously misinterpreted the external interference signal as a physiological signal. Only cases without any recorded ‘‘heart activity’’ and with nominal pacing rates (as expected from the program parameter settings) of the implants were rated as ‘‘interference-free.’’ Exposure to the whole body mat (peak magnetic induction up to 265 mT) did not show an influence on PMs and AICD in any case. The cushion applicator at the highest field intensity (peak magnetic induction up to 360 mT) led to atrial sensing defects in four PM models with unipolar electrode configuration. Under bipolar electrode configuration no disturbances occurred. The bar applicator led to sensing problems and consecutively reduced pacing rates in alltested PM models under unipolar electrode configuration and maximum field intensity (peak magnetic induction up to 980 mT). Bipolar electrode configuration resolved the problem. The investigated AICDs did not show malfunctions under any investigated condition. In conclusion, the examined PEMF therapy system did not interfere with the investigated implantable cardiac devices with bipolar electrode configuration. However, unipolar electrode configuration in pacemakers seems to be potentially hazardous during application of the examined PEMF therapy system. Bioelectromagnetics 27:365–377, 2006. ! 2006 Wiley-Liss, Inc.

Insights Into Electromagnetic Interaction Mechanisms

REBA GOODMAN AND MARTIN BLANK. Insights Into Electromagnetic Interaction Mechanisms. JOURNAL OF CELLULAR PHYSIOLOGY 192:16–22 (2002)

Low frequency (<300 Hz) electromagnetic (EM) fields induce biological changes that include effects ranging from increased enzyme reaction rates to increased transcript levels for specific genes. The induction of stress gene HSP70 expression by exposure to EM fields provides insight into how EM fields interact with cells and tissues. Insights into the mechanism(s) are also provided by examination of the interaction of EM fields with moving charges and their influence on enzyme reaction rates in cell-free systems. Biological studies with in vitro model systems have focused, in general, on the nature of the signal transduction pathways involved in response to EM fields. It is likely, however, that EM fields also interact directly with electrons in DNA to stimulate biosynthesis. Identification of an EM field-sensitive DNA sequence in the heat shock 70 (HSP70) promoter, points to the application of EM fields in two biomedical applications: cytoprotection and gene therapy. EM field induction of the stress protein hsp70 may also provide a useful biomarker for establishing a science-based safety standard for the design of cell phones and their transmission towers. J. Cell. Physiol. 192: 16–22, 2002. 2002 Wiley-Liss, Inc.

New Mechanisms of Biological Effects of Electromagnetic Fields

A. L. Buchachenkoaa, D. A. Kuznetsovb, and V. L. Berdinskya. New Mechanisms of Biological Effects of Electromagnetic Fields
a, Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region, 142432 Russia
b,
Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991 Russia

Abstract—ATP production in mitochondria depends on the nuclear spin and magnetic moment of Mg2+ ion in creatine kinase and ATPase. Consequently, the enzymatic synthesis of ATP is an ion-radical process and depends on the external magnetic field and microwave fields that control the spin states of ion-radical pairs and influence the ATP synthesis. The chemical mechanism of ATP synthesis and the origin of biological effects of electromagnetic (microwave) fields are discussed.
Key words: phosphorylation, ATP, creatine kinase, electromagnetic fields, spin chemistry

Historical evidence that electrification caused the 20th century

Milham S. Historical evidence that electrification caused the 20th century epidemic of “diseases of civilization”. Med Hypotheses 2010 Mar; 74(3):615-6.

The slow spread of residential electrification in the US is the first half of the 20th century from urban to rural areas resulted by 1940 in two large populations; urban populations, with nearly complete electrification and rural populations exposed to varying levels of electrification depending on the progress of electrification in their state. It took until 1956 for US farms to reach urban and rural non-farm electrification levels. Both populations were covered by the US vital registration system. US vital statistics tabulations and census records for 1920-1960, and historical US vital statistics documents were examined. Residential electrification data were available in the US census of population for 1930, 1940 and 1950. Crude urban and rural death rates were calculated, and death rates by state were correlated with electrification rates by state for urban and rural areas for 1940 white resident deaths. Urban death rates were much higher than rural rates for cardiovascular diseases, malignant diseases, diabetes and suicide in 1940. Rural death rates were significantly correlated with the level of residential electric service by state for most causes examined. I hypothesize that the 20th century epidemic of the so called diseases of civilization including cardiovascular disease, cancer and diabetes and suicide was caused by electrification not by lifestyle. A large proportion of these diseases may therefore be preventable.

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